The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2019
Filed:
Aug. 29, 2017
Applicant:
Wake Forest University Health Sciences, Winston-Salem, NC (US);
Inventors:
Emmanuel C. Opara, Durham, NC (US);
Benjamin S. Harrison, Tobaccoville, NC (US);
Assignee:
WAKE FOREST UNIVERSITY HEALTH SCIENCES, Winston-Salem, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/39 (2015.01); C12N 5/071 (2010.01); A61K 45/06 (2006.01); A61K 9/50 (2006.01); A61K 9/00 (2006.01); A61K 47/22 (2006.01); A61K 38/18 (2006.01); A61K 47/02 (2006.01); A61K 47/42 (2017.01); A61K 38/44 (2006.01); A61K 31/555 (2006.01); A61K 33/40 (2006.01); C12N 1/04 (2006.01); C12N 11/10 (2006.01); C12N 11/04 (2006.01);
U.S. Cl.
CPC ...
A61K 35/39 (2013.01); A61K 9/0024 (2013.01); A61K 9/501 (2013.01); A61K 9/5015 (2013.01); A61K 9/5036 (2013.01); A61K 9/5073 (2013.01); A61K 31/555 (2013.01); A61K 33/40 (2013.01); A61K 38/1866 (2013.01); A61K 38/44 (2013.01); A61K 45/06 (2013.01); A61K 47/02 (2013.01); A61K 47/22 (2013.01); A61K 47/42 (2013.01); C12N 1/04 (2013.01); C12N 5/0676 (2013.01); C12N 11/04 (2013.01); C12N 11/10 (2013.01);
Abstract
Microcapsules are described that comprise (a) a liquid aqueous or hydrogel core; (b) a semipermeable membrane surrounding said core; (c) live animal cells (e.g., pancreatic cells) in the core; and (d) oxygen-generating particles in said core, said oxygen-generating particles included in said microcapsules in an amount sufficient to lengthen the duration of viability of said animal cells in said microcapsules. Compositions comprising such microcapsules and uses thereof, such as in treating diabetes, are also described.