The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 09, 2019

Filed:

Dec. 11, 2017
Applicant:

Amylyx Pharmaceuticals Inc., Cambridge, MA (US);

Inventors:

Joshua Cohen, Canton, MA (US);

Justin Klee, Cambridge, MA (US);

Assignee:

Amylyx Pharmaceuticals Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/192 (2006.01); A61K 31/575 (2006.01);
U.S. Cl.
CPC ...
A61K 31/575 (2013.01); A61K 31/192 (2013.01);
Abstract

This invention relates to methods and compositions for use improving cell viability, particularly neural cell viability, and more particularly to methods and compositions for use improving cell viability by reducing reactive oxygen metabolite-mediated oxidative damage in a cell, regulating redox homeostasis in a cell, or reducing mitochondrial dysfunction in a cell. The invention further relates to the administration of the bile acid tauroursodeoxycholic acid (TUDCA) in combination with phenylbutyric Acid (PBA) to improve cell viability, and treat at least one symptom associated with, prevent the time of onset of, or slow the development of a disease related to oxidative stress.


Find Patent Forward Citations

Cohen, Joshua. (2019). Compositions for improving cell viability and methods of use thereof (U.S. Patent No. 10251896). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10251896

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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