The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2019
Filed:
Mar. 02, 2016
Applicant:
Stc.unm, Albuquerque, NM (US);
Inventors:
Eric R. Prossnitz, Albuquerque, NM (US);
Matthias Barton, Zurich, CH;
Matthias R. Meyer, Stallikon, CH;
Assignee:
STC.UNM, Albuquerque, NM (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/436 (2006.01); A61K 31/435 (2006.01); A61K 31/4355 (2006.01); A61K 31/437 (2006.01); A61K 31/16 (2006.01); A61K 31/7088 (2006.01); A61K 38/28 (2006.01);
U.S. Cl.
CPC ...
A61K 31/436 (2013.01); A61K 31/16 (2013.01); A61K 31/435 (2013.01); A61K 31/437 (2013.01); A61K 31/4355 (2013.01); A61K 31/7088 (2013.01); A61K 38/28 (2013.01); G01N 2800/042 (2013.01);
Abstract
The current invention is in the field of molecular biology/pharmacology and provides methods of using compounds that modulate the effects of GPR30/GPER for treating obesity and diabetes (preferably agonists) as well as disease states and/or conditions that result from excessive formation of reactive oxygen species (preferably antagonists). These compounds may function as agonists and/or antagonists of the disclosed estrogen receptor and/or modulate the expression/upregulation of nox and nox-associated reactive oxygen species (ROS).