The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 09, 2019

Filed:

Jan. 22, 2018
Applicant:

Novartis Ag, Basel, CH;

Inventors:

Jun Cao, Changshu, CN;

Bernhard Erb, Gipf-Oberfrick, CH;

Robin Alec Fairhurst, Riehen, CH;

Arnaud Grandeury, Helfrantzkirch, FR;

Shinji Hatakeyama, Basel, CH;

Magdalena Koziczak-Holbro, Basel, CH;

Xinzhong Lai, Changshu, CN;

Philipp Lustenberger, Allschwil, CH;

Bernd Ulrich Riebesehl, Loerrach, DE;

Nicola Tufilli, Moehlin, CH;

Thomas Ullrich, Bottmingen, CH;

Xiang Wu, Changshu, CN;

Jianguang Zhou, Suzhou, CN;

Assignee:

NOVARTIS AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/428 (2006.01); A61K 31/167 (2006.01); C07D 277/68 (2006.01); C07C 53/10 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/428 (2013.01); A61K 31/167 (2013.01); A61K 45/06 (2013.01); C07C 53/10 (2013.01); C07D 277/68 (2013.01); C07B 2200/07 (2013.01); Y02P 20/55 (2015.11);
Abstract

The present invention provides a compound of formula (I) in free form or in pharmaceutically acceptable salt form a method for manufacturing the compound of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and pharmaceutical compositions.


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