The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2019
Filed:
Apr. 11, 2017
Applicant:
Children's Hospital Medical Center, Cincinnati, OH (US);
Inventors:
Bruce Trapnell, Mariemont, OH (US);
Tony Sallese, Eaton, OH (US);
Brenna Carey, Cincinnati, OH (US);
Takuji Suzuki, Midori, JP;
Assignee:
Children's Hospital Medical Center, Cincinnati, OH (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/18 (2006.01); A61K 9/00 (2006.01); A61K 31/4439 (2006.01); A61K 47/10 (2017.01); A61K 47/26 (2006.01); A61K 9/08 (2006.01);
U.S. Cl.
CPC ...
A61K 31/18 (2013.01); A61K 9/007 (2013.01); A61K 9/0053 (2013.01); A61K 9/08 (2013.01); A61K 31/4439 (2013.01); A61K 47/10 (2013.01); A61K 47/26 (2013.01);
Abstract
Disclosed are compositions and methods for treating a condition characterized by a dysregulation in macrophage lipid homeostasis. The disclosed methods may include the administration of an agent selected from a PPARγ agonist, a LXR agonist, or a combination thereof. In certain aspects, the disclosed methods may be used to prevent, treat, or ameliorate conditions such as pulmonary alveolar proteinosis (PAP) and/or symptoms associated therewith.