IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10251847 B1

PDFFull Text
Date of Patent:
Apr. 09, 2019

Filed:

Dec. 16, 2015

Polymorphic and amorphous forms of (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide

Applicant:

Bioelectron Technology Corporation, Mountain View, CA (US);

Inventors:

Paul Mollard, Mountain View, CA (US);

Christopher R. Cornell, Mountain View, CA (US);

Kieron E. Wesson, Mountain View, CA (US);

Peter Giannousis, Mountain View, CA (US);

Shazad Suchit, Devens, MA (US);

Mahmoud Mirmehrabi, Halifax, CA;

Assignee:

BIOELECTRON TECHNOLOGY CORPORATION, Mountain View, CA (US);

Attorney:

Squire Patton Boggs (US) LLP

Primary Examiner:

Rebecca L Anderson

Int. Cl.
CPC ...
C07C 215/08 (2006.01); C07C 215/18 (2006.01); C07C 215/30 (2006.01); C07C 231/12 (2006.01); C07C 235/78 (2006.01); A61K 31/164 (2006.01); A61K 31/122 (2006.01); C07C 215/28 (2006.01); C07B 57/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/122 (2013.01); A61K 31/164 (2013.01); C07B 57/00 (2013.01); C07C 215/08 (2013.01); C07C 215/28 (2013.01); C07C 215/30 (2013.01); C07C 231/12 (2013.01); C07C 235/78 (2013.01); C07B 2200/13 (2013.01); C07C 2601/16 (2017.05);
Abstract

Disclosed herein are polymorphic and amorphous forms of anhydrate, hydrate, and solvates of (R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide and methods of using such compositions for treating or suppressing oxidative stress disorders, including mitochondrial disorders, impaired energy processing disorders, neurodegenerative diseases and diseases of aging. Further disclosed are methods of making such polymorphic and amorphous forms.

Find Patent Forward Citations

Loading…