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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10251824 B1

PDFFull Text
Date of Patent:
Apr. 09, 2019

Filed:

Dec. 13, 2016

Method for inducing pluripotent stem cells and pluripotent stem cells prepared by said method

Applicants:

Amorepacific Corporation, Seoul, KR;

Snu R&db Foundation, Seoul, KR;

Inventors:

Ah Reum Kim, Yongin-si, KR;

Su Na Kim, Yongin-si, KR;

Won Seok Park, Yongin-si, KR;

Yoo Wook Kwon, Seoul, KR;

Young Bae Park, Seoul, KR;

Hyo Soo Kim, Seoul, KR;

Jae Seung Paek, Ansan-si, KR;

Assignees:

AMOREPACIFIC CORPORATION, Seoul, KR;

SNU R&DB FOUNDATION, Seoul, KR;

Attorney:

Cantor Colburn LLP

Primary Examiner:

Dennis Heyer

Assistant Examiner:

Daniel M Podgorski

Int. Cl.
CPC ...
A61K 8/365 (2006.01); A61Q 19/00 (2006.01); A23L 33/105 (2016.01); A61K 35/28 (2015.01); C12N 5/074 (2010.01); A61K 31/191 (2006.01); A61K 36/14 (2006.01); A61Q 19/08 (2006.01); A61K 8/368 (2006.01); A61K 8/97 (2017.01); A23L 33/10 (2016.01); A23L 2/52 (2006.01); A61K 8/02 (2006.01); A61K 8/06 (2006.01); A61K 8/11 (2006.01); A61K 8/98 (2006.01); A61K 9/00 (2006.01); A61K 9/14 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01);
U.S. Cl.
CPC ...
A61K 8/365 (2013.01); A23L 2/52 (2013.01); A23L 33/10 (2016.08); A23L 33/105 (2016.08); A61K 8/0204 (2013.01); A61K 8/0216 (2013.01); A61K 8/0225 (2013.01); A61K 8/06 (2013.01); A61K 8/11 (2013.01); A61K 8/368 (2013.01); A61K 8/97 (2013.01); A61K 8/981 (2013.01); A61K 9/0019 (2013.01); A61K 9/0056 (2013.01); A61K 9/0095 (2013.01); A61K 9/14 (2013.01); A61K 9/20 (2013.01); A61K 9/48 (2013.01); A61K 31/191 (2013.01); A61K 35/28 (2013.01); A61K 36/14 (2013.01); A61Q 19/00 (2013.01); A61Q 19/08 (2013.01); C12N 5/0696 (2013.01); A23V 2002/00 (2013.01); A61K 2800/74 (2013.01); A61K 2800/78 (2013.01); A61K 2800/91 (2013.01); A61K 2800/92 (2013.01); C12N 2500/14 (2013.01); C12N 2500/76 (2013.01); C12N 2501/115 (2013.01); C12N 2501/603 (2013.01); C12N 2501/73 (2013.01); C12N 2502/02 (2013.01); C12N 2502/13 (2013.01); C12N 2506/02 (2013.01); C12N 2506/1307 (2013.01); C12N 2533/54 (2013.01);
Abstract

The present disclosure relates to a method for inducing pluripotent stem cells by inducing reprogramming and/or dedifferentiation of differentiated adult cells using shikimic acid, a plant extract or plant stem cells containing shikimic acid and an extract of dedifferentiated stem cells (callus), pluripotent stem cells prepared by the method and a composition containing the pluripotent stem cells. In accordance with the present disclosure, ethical concerns implicated with the use of eggs to prepare pluripotent stem cells such as embryonic stem cell can be resolved. And, because the plant stem cell extract unharmful to human is used, pluripotent stem cells with proven safety can be prepared and they may be used to develop immunocompatible cell therapy agents suited for individuals. In addition, by pluripotent stem cells from individuals having diseases, the present disclosure will be very useful in studying the cause of diseases and devolving therapeutic strategy.

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