The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2019
Filed:
Jun. 10, 2015
Applicant:
Blueprint Medicines Corporation, Cambridge, MA (US);
Inventors:
Nicolas Stransky, Charlestown, MA (US);
Joseph L. Kim, Wayland, MA (US);
Assignee:
Blueprint Medicines Corporation, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); C07K 14/47 (2006.01); C12N 15/11 (2006.01); C12Q 1/48 (2006.01); C12N 9/12 (2006.01); G01N 33/574 (2006.01); C12N 9/02 (2006.01); C07K 16/40 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C07K 14/4721 (2013.01); C07K 16/40 (2013.01); C12N 9/001 (2013.01); C12N 9/12 (2013.01); C12N 15/11 (2013.01); C12Q 1/485 (2013.01); C12Y 103/01093 (2015.07); C12Y 207/11013 (2013.01); G01N 33/57423 (2013.01); G01N 33/57438 (2013.01); G01N 33/57496 (2013.01); C07K 2319/00 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/47 (2013.01); G01N 2333/90206 (2013.01); G01N 2333/912 (2013.01); G01N 2333/9121 (2013.01); G01N 2500/04 (2013.01); G01N 2500/10 (2013.01); G01N 2800/52 (2013.01);
Abstract
The invention provides to PKN1 gene fusions, PKN1 fusion proteins, and fragments of those genes and polypeptides. The invention further provides methods of diagnosing and treating diseases or disorders associated with PKN1 fusions, such as conditions mediated by aberrant PKN1 expression or activity, or over expression of PKN1.