The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2019
Filed:
Mar. 28, 2018
Arizona Board of Regents on Behalf of Arizona State University, Scottsdale, AZ (US);
Bo Wang, Tempe, AZ (US);
Weiwen Zhang, Chandler, AZ (US);
Deirdre Meldrum, Phoenix, AZ (US);
David Nielsen, Tempe, AZ (US);
ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY, Scottsdale, AZ (US);
Abstract
Construction and expression of synthetic pathways to produce (S) or (R)-3-hydroxybutyrate (3HB) as enantiomerically-pure products by genetically engineering cyanobacteriumsp. PCC 6803. Under optimized growth conditions, the pathway employing phaA and phaB fromwas the most effective, producing up to 533.4±5.5 mg/l (R)-3HB after 21 days photosynthetic cultivation. For the first time, the feasibility and high efficiency of producing 3HB using solar energy and COas sole energy and carbon sources by engineered cyanobacteria is demonstrated.