The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2019
Filed:
Sep. 21, 2015
Applicants:
Biomarin Technologies B.v., Leiden, NL;
Academisch Ziekenhuis Leiden, Leiden, NL;
Inventors:
Gerard Johannes Platenburg, Voorschoten, NL;
Josephus Johannes de Kimpe, Utrecht, NL;
Judith Christina Theodora van Deutekom, Dordrecht, NL;
Garrit-Jan Boudewijn van Ommen, Amsterdam, NL;
Annemieke Aartsma-Rus, Hoofddorp, NL;
Assignees:
Biomarin Technologies B.V., Leiden, NL;
Academisch Ziekenhuis Leiden, Leiden, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/113 (2010.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 48/00 (2013.01); C12N 2310/11 (2013.01); C12N 2310/111 (2013.01); C12N 2310/314 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/3233 (2013.01); C12N 2310/346 (2013.01); C12N 2310/3513 (2013.01); C12N 2310/3517 (2013.01); C12N 2320/33 (2013.01);
Abstract
The invention relates to a nucleic acid molecule that binds and/or is complementary to the nucleotide molecule having sequence 5'-GUGGCUAACAGAAGCU (SEQ ID NO 1) and to its use in a method for inducing skipping of exon 44 of the DMD gene in a DMD patient.