The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2019

Filed:

Mar. 02, 2015
Applicant:

The University of Tokyo, Tokyo, JP;

Inventors:

Hiromitsu Nakauchi, Tokyo, JP;

Hideki Masaki, Tokyo, JP;

Hideyuki Murayama, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/02 (2006.01); C12N 15/74 (2006.01); C12N 5/0735 (2010.01); A01K 67/027 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0606 (2013.01); A01K 67/0271 (2013.01); C12N 15/85 (2013.01); A01K 2207/12 (2013.01); C12N 2501/235 (2013.01); C12N 2501/415 (2013.01); C12N 2501/58 (2013.01); C12N 2501/60 (2013.01); C12N 2510/00 (2013.01);
Abstract

The present invention provides a method for putting a primed pluripotent stem cell in a less differentiated state, a method for producing a pluripotent stem cell having an improved chimera forming ability from a primed pluripotent stem cell, and a method for producing a chimeric animal by using the pluripotent stem cell obtained by any of these methods. The present invention also provides a composition containing a Wnt/β catenin signal inhibitor.


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