The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2019
Filed:
Aug. 04, 2014
Applicant:
Rigshospitalet Copenhagen University Hospital, Copenhagen Ø, DK;
Inventor:
Martin Blomberg Jensen, Copenhagen Ø, DK;
Assignee:
RIGSHOSPITALET COPENHAGEN UNIVERSITY HOSPITAL, Copenhagen Ø, DK;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 16/00 (2006.01); A61K 38/00 (2006.01); C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2875 (2013.01); A61K 38/1793 (2013.01); A61K 39/395 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/76 (2013.01);
Abstract
The present invention relates to antagonists or inhibitors, which bind selectively to RANKL/OPGbp and regulate the interaction between RANKL/OPGbp and RANK/OPG. In particular, the present invention relates to an antibody or antigen binding domain, fragment or derivative thereof, immunoreactive with a RANKL/OPGbppeptide for use in the treatment, prevention or alleviation of male infertility or reduced male fertility such as oligospermia or azospermia.