The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2019

Filed:

Apr. 03, 2018
Applicant:

Xoc Pharmaceuticals, Inc., Los Gatos, CA (US);

Inventors:

Thomas Armer, Los Altos, CA (US);

Geoff McKinley, Mountain View, CA (US);

Scott Borland, Los Gatos, CA (US);

Miguel Guzman, Cupertino, CA (US);

Ármin Szabolcs, Szombathely, HU;

János Gerencser, Budapest, HU;

Assignee:

XOC PHARMACEUTICALS, INC., Los Gatos, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 457/06 (2006.01); A61K 31/48 (2006.01); C07D 471/06 (2006.01); C07D 495/06 (2006.01);
U.S. Cl.
CPC ...
C07D 471/06 (2013.01); C07D 495/06 (2013.01);
Abstract

Provided herein are ergoline compounds and pharmaceutical compositions thereof. In some embodiments, provided herein are methods of treatment, prevention, or amelioration of a variety of medical disorders such as, for example, migraine using the compounds and pharmaceutical compositions disclosed herein. In still other embodiments, provided herein are methods of agonizing receptors such as, for example, the 5-HT, 5-HTand 5-HTreceptors without agonizing the 5-HTreceptor using the compounds and pharmaceutical compositions disclosed herein. In still other embodiments, provided herein are methods of antagonizing the 5-HTadrenergic alphaand/or the alphareceptors using the compounds and pharmaceutical compositions disclosed herein. In still other embodiments, provided herein are methods of antagonizing the D2 and D3 receptor using the compounds and pharmaceutical compositions disclosed herein.


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