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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10246440 B1

PDFFull Text
Date of Patent:
Apr. 02, 2019

Filed:

Dec. 18, 2015

Indazole sulfonamide derivatives as inverse agonists of retinoid-related orphan receptor gamma (ror γ (t))

Applicant:

Galderma Research & Development, Biot, FR;

Inventors:

Branislav Musicki, Nice, FR;

Gilles Ouvry, Biot, FR;

Etienne Thoreau, Saint Vallier de Thiey, FR;

Claire Bouix-Peter, Vallauris, FR;

Assignee:

GALDERMA RESEARCH & DEVELOPMENT, Biot, FR;

Attorneys:

Sunit Talapatra

Foley & Lardner LLP

Primary Examiner:

Venkataraman Balasubramanian

Int. Cl.
CPC ...
C07D 231/56 (2006.01); C07D 401/06 (2006.01); C07D 403/04 (2006.01); C07D 405/04 (2006.01); C07D 405/06 (2006.01); C07D 405/14 (2006.01); C07D 413/06 (2006.01); A61K 31/416 (2006.01); A61P 17/06 (2006.01); C07D 215/36 (2006.01); C07D 401/04 (2006.01); C07D 403/06 (2006.01); C07D 405/12 (2006.01); C07D 407/04 (2006.01); C07D 409/04 (2006.01); C07D 409/06 (2006.01); C07D 417/06 (2006.01); C07D 471/10 (2006.01); C07D 209/34 (2006.01); C07D 307/79 (2006.01); A61P 17/10 (2006.01); A61P 17/04 (2006.01);
U.S. Cl.
CPC ...
C07D 405/06 (2013.01); A61P 17/04 (2018.01); A61P 17/06 (2018.01); A61P 17/10 (2018.01); C07D 209/34 (2013.01); C07D 215/36 (2013.01); C07D 231/56 (2013.01); C07D 307/79 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 403/04 (2013.01); C07D 403/06 (2013.01); C07D 405/04 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 407/04 (2013.01); C07D 409/04 (2013.01); C07D 409/06 (2013.01); C07D 413/06 (2013.01); C07D 417/06 (2013.01); C07D 471/10 (2013.01);
Abstract

Indazole sulfonamide derivatives of formula (I), the pharmaceutically acceptable addition salts thereof, the hydrates and/or solvates thereof, and the use of same as inverse agonists of retinoid-related orphan receptor gamma RORγt are described. Pharmaceutical compositions including such compounds, as well as the use thereof for the topical and/or oral treatment of RORγt receptor-mediated inflammatory diseases, in particular acne, psoriasis and/or atopic dermatitis are also described.

Find Patent Forward Citations

Musicki, Branislav. (2019). Indazole sulfonamide derivatives as inverse agonists of retinoid-related orphan receptor gamma (ror γ (t)) (U.S. Patent No. 10246440). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10246440

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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