The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2019

Filed:

Jun. 08, 2016
Applicant:

Crystal Pharmatech Co., Ltd., Suzhou, Jiangsu, CN;

Inventors:

Minhua Chen, Jiangsu, CN;

Yanfeng Zhang, Jiangsu, CN;

Xiaojuan Diao, Jiangsu, CN;

Xiaoyu Zhang, Jiangsu, CN;

Assignee:

Crystal Pharmatech Co., Ltd., Suzhou, Jiangsu, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/48 (2006.01); A61K 31/47 (2006.01); A61P 35/00 (2006.01); C07C 255/03 (2006.01);
U.S. Cl.
CPC ...
C07D 215/48 (2013.01); A61K 31/47 (2013.01); A61P 35/00 (2018.01); C07B 2200/13 (2013.01); C07C 255/03 (2013.01);
Abstract

The present disclosure relates to a novel crystalline form of lenvatinib mesylate and the preparation method thereof. The novel crystalline form of mesylate of the present disclosure can be used for treating invasive and differentiated thyroid cancer. The novel crystalline form of mesylate of the present disclosure has good solubility, stability, and remarkable purification effect in process. The preparation method of this novel crystalline form is simple, low cost, and has an important value for future optimization and development of the drug.


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