The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2019

Filed:

Apr. 01, 2015
Applicants:

The University of Queensland, St. Lucia, Queensland, AU;

Monash University, Clayton, Victoria, AU;

The University of Melbourne, Victoria, AU;

Inventors:

Alexandra Jane Corbett, Victoria, AU;

James McCluskey, Victoria, AU;

Lars Kjer-Nielsen, Victoria, AU;

Zhenjun Chen, Victoria, AU;

Jamie Rossjohn, Victoria, AU;

Onisha Patel, Victoria, AU;

Richard William Birkinshaw, Victoria, AU;

Sidonia Barbara Guiomar Eckle, Victoria, AU;

David Paul Fairlie, Queensland, AU;

Ligong Liu, Queensland, AU;

Jeffrey Yam Wing Mak, Queensland, AU;

Assignees:

The University of Queensland, St. Lucia, AU;

Monash University, Clayton, AU;

The University of Melbourne, Victoria, AU;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/54 (2006.01); A61K 31/513 (2006.01); C07D 239/545 (2006.01); C07K 14/74 (2006.01); C07D 239/60 (2006.01); G01N 33/569 (2006.01); A61K 47/55 (2017.01); A61K 47/64 (2017.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/513 (2013.01); A61K 47/55 (2017.08); A61K 47/6425 (2017.08); C07D 239/54 (2013.01); C07D 239/545 (2013.01); C07D 239/60 (2013.01); C07K 14/70539 (2013.01); G01N 33/56972 (2013.01); A61K 38/00 (2013.01); G01N 2333/70539 (2013.01); G01N 2800/26 (2013.01);
Abstract

The present invention provides ligands which bind to MR1, some of which induce MR1 to bind to MAIT cells thereby activating or inhibiting MAIT cell activation.


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