The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2019
Filed:
Oct. 10, 2013
H. Lee Moffitt Cancer Center and Research Institute, Inc., Tampa, FL (US);
Pearlie Burnette, Tampa, FL (US);
Jessica M. McDaniel, Etna, OH (US);
H. Lee Moffitt Cancer Center and Research Institute, Inc., Tampa, FL (US);
Abstract
Disclosed are compositions and methods for predicting responsiveness of a subject to treatment with lenalidomide (LEN) by assaying a sample from the subject for surface expression of CD28 on T-cells. Also provided is a method of treating a subject for cancer that involves assaying a sample from the subject for surface expression of CD28 on T-cells and then treating them with LEN if they do not have reduced CD28 surface expression on the T-cells. Also provided is a method for promoting responsiveness of a subject to LEN by administering to the subject a composition that promotes expression of CD28 on the surface of T-cells.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile