The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 26, 2019

Filed:

Oct. 17, 2014
Applicant:

Washington University IN St. Louis, St. Louis, MO (US);

Inventors:

Srikanth Singamaneni, St. Louis, MO (US);

Limei Tian, St. Louis, MO (US);

Keng-Ku Liu, Philadelphia, PA (US);

Abdennour Abbas, St. Louis, MO (US);

Jeremiah J. Morrissey, St. Louis, MO (US);

Evan D. Kharasch, St. Louis, MO (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/553 (2006.01); G01N 33/543 (2006.01); B82Y 15/00 (2011.01); G01N 21/65 (2006.01); B82Y 40/00 (2011.01); B82Y 30/00 (2011.01);
U.S. Cl.
CPC ...
G01N 33/54373 (2013.01); B82Y 15/00 (2013.01); G01N 21/658 (2013.01); G01N 33/54346 (2013.01); G01N 33/553 (2013.01); B82Y 30/00 (2013.01); B82Y 40/00 (2013.01);
Abstract

Plasmonic nanotransducers, methods of preparing plasmonic nanotransducers, and methods for label-free detection of target molecules are disclosed. The plasmonic nanotransducers include hollow nanostructure cores and artificial antibodies. The plasmonic nanotransducers are exposed to a biological sample that can contain the specific target molecules. The plasmonic nanotransducers can be analyzed with surface enhanced Raman scattering techniques and/or localized surface plasmon resonance techniques to quantify the amount of the target molecule in the sample.


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