The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2019
Filed:
Mar. 28, 2017
Technion Research & Development Foundation Ltd., Haifa, IL;
Roee Amit, Haifa, IL;
Alexey Tomsov, Karmiel, IL;
Orna Atar, Haifa, IL;
Liron Abrahami, Kibbutz Ma'agan Michael, IL;
Yael Annis, Hashmonaim, IL;
Roni Cohen, Zikhron Ya'akov, IL;
Alexandra Ereskovsky, Nesher, IL;
Noa Katz, Haifa, IL;
Lior Levy, Haifa, IL;
Maayan Lufton, Kiryat Yam, IL;
Tal Ofek, Haifa, IL;
Sagi Sheinkman, Netanya, IL;
Nitzan Shmuel, Nofit, IL;
Inbal Vaknin, Or Akiva, IL;
Ruth Veksler, Karmiel, IL;
Adi Yannai, Haifa, IL;
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD., Haifa, IL;
Abstract
Chimeric polypeptides comprising a dihydrotestosterone (DHT) reductase moiety, such as 3 alpha-hydroxysteroid dehydrogenase (3α-HSD), fused to a signal peptide moiety, polynucleotides encoding same, and compositions comprising at least one microorganism cell capable of secreting the chimeric polypeptide, are provided. Further provided are methods and kits for treating, preventing or ameliorating androgen-dependent disorders, including but not limited to androgenic alopecia.