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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10240130 B1

PDFFull Text
Date of Patent:
Mar. 26, 2019

Filed:

Feb. 15, 2018

Cdna clone-launched platform for high-yield production of inactivated zika virus

Applicant:

The Board of Regents of the University of Texas System, Austin, TX (US);

Inventors:

Xuping Xie, Galveston, TX (US);

Chao Shan, Galveston, TX (US);

Pei-Yong Shi, Galveston, TX (US);

Assignee:

THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US);

Attorneys:

Robin L. Teskin

LeClairRyan PLLC

Primary Examiner:

Barry A Chestnut

Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/12 (2006.01); C07K 14/005 (2006.01); C12N 7/00 (2006.01); A61K 31/70 (2006.01); A61P 31/14 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); A61K 39/12 (2013.01); A61P 31/14 (2018.01); A61K 2039/5252 (2013.01); A61K 2039/5254 (2013.01); A61K 2039/552 (2013.01); A61K 2039/575 (2013.01); C12N 2770/24121 (2013.01); C12N 2770/24122 (2013.01); C12N 2770/24134 (2013.01); C12N 2770/24171 (2013.01);
Abstract

The invention generally relates to the development of variant Zika strains, cDNA clones and mRNA transcripts that contain specific mutations in the Zika ORF, and methods for producing high yields of Zika viruses ('ZIKVs') using these variant cDNA clones, transcripts and strains. The produced ZIKVs can be used for the manufacture of purified inactivated vaccines (PIVs), which may be useful for treating ZIKV-related diseases and for providing immunoprotection against ZIKV.

Find Patent Forward Citations

Xie, Xuping. (2019). Cdna clone-launched platform for high-yield production of inactivated zika virus (U.S. Patent No. 10240130). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10240130

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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