The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2019
Filed:
Feb. 09, 2015
Katholieke Universiteit Leuven, Leuven, BE;
Inserm (Institut National DE LA Santé ET DE LA Recherche Médicale), Paris, FR;
Université DE Caen Basse Normandie, Caen, FR;
Centre Hospitalier Universitaire DE Caen, Caen, FR;
Paul Declerck, Leuven, BE;
Simon De Meyer, Leuven, BE;
Nick Geukens, Leuven, BE;
Ann Gils, Leuven, BE;
Marina Rubio, Caen, FR;
Denis Vivien, Caen, FR;
Tine Wyseure, Leuven, BE;
KATHOLIEKE UNIVERSITEIT LEUVEN, Leuven, BE;
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), Paris, FR;
UNIVERSITÉ DE CAEN BASSE NORMANDIE, Caen, FR;
CENTRE HOSPITALIER UNVIERSITAIRE DE CAEN, Caen, FR;
Abstract
Disclosed herein is a bispecific inhibitor for use in treating thrombotic disorders, such as acute thrombotic disorders like stroke and thromboembolism. The bispecific inhibitor is based on monoclonal antibodies targeting TAFI and PAI-1, and shows efficacy in the presence or the absence of plasminogen activators such as tissue-type plasminogen activator (tPA).