The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2019
Filed:
Jun. 01, 2017
Applicant:
Philogen S.p.a., Siena, IT;
Inventors:
Giovanni Neri, Sovicille, IT;
Kathrin Schwager, Zurich, CH;
Melanie C. Ruzek, Cambridge, MA (US);
Denise M. O'hara, Andover, MA (US);
Jianqing Chen, Andover, MA (US);
Assignee:
PHILOGEN S.P.A., Siena, IT;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); A61K 38/06 (2006.01); A61K 39/395 (2006.01); A61K 38/07 (2006.01); A61K 38/08 (2019.01); A61K 38/20 (2006.01); A61K 47/68 (2017.01); C07K 14/54 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 38/06 (2013.01); A61K 38/07 (2013.01); A61K 38/08 (2013.01); A61K 38/2066 (2013.01); A61K 47/6843 (2017.08); A61K 39/3955 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/626 (2013.01);
Abstract
Specific binding members that bind the ED-A isoform of fibronectin for use in methods of treatment, diagnosis, detection and/or imaging of inflammatory bowel disease (IBD), and/or for use in delivery to the IBD tissue of a molecule conjugated to the specific binding member. The specific binding member may, for example, be conjugated to an immunosupressive or anti-inflammatory molecule, such as interleukin-10.