The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 26, 2019

Filed:

May. 26, 2016
Applicant:

The Regents of the University of Michigan, Ann Arbor, MI (US);

Inventors:

David H. Sherman, Ann Arbor, MI (US);

Fengan Yu, Ann Arbor, MI (US);

Chuanwu Xi, Ann Arbor, MI (US);

Jianfeng Wu, Ann Arbor, MI (US);

Pamela J. Schultz, Superior Township, MI (US);

Ashootosh Tripathi, Ypsilanti, MI (US);

Sung Ryeol Park, Ann Arbor, MI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 4/00 (2006.01); C07K 7/06 (2006.01); A01N 37/46 (2006.01); A01N 43/76 (2006.01); C07K 5/00 (2006.01); C07K 5/083 (2006.01); C07K 5/103 (2006.01); C07D 413/12 (2006.01); A61K 38/07 (2006.01); A61K 45/06 (2006.01); C07K 14/195 (2006.01); C12N 9/88 (2006.01);
U.S. Cl.
CPC ...
C07K 7/06 (2013.01); A01N 37/46 (2013.01); A01N 43/76 (2013.01); A61K 38/07 (2013.01); A61K 45/06 (2013.01); C07D 413/12 (2013.01); C07K 5/00 (2013.01); C07K 5/081 (2013.01); C07K 5/1013 (2013.01); C07K 14/195 (2013.01); C12N 9/88 (2013.01); C12Y 402/99021 (2013.01);
Abstract

Provided herein are biofilm inhibitors obtained from marine microbial derived natural product extracts from, resulting in biofilm inhibitors, cahuitamycins. Also provided are mutant, methods of inhibiting biofilm formation, methods of producing, or increasing the production of, cahuitamycins, methods for synthesizing cahuitamycins, and methods of purifying cahuitamycins.


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