The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2019
Filed:
Oct. 20, 2016
Université DE Montréal, Montréal, CA;
Claude Perreault, Outremont, CA;
Pierre Thibault, Ile-Bizzard, CA;
Sébastien Lemieux, LaSalle, CA;
Diana Paola Granados, Montréal, CA;
Sriranganadane Dev, Montréal, CA;
Mohamed Tariq Daouda, Montréal, CA;
Olivier Caron-Lizotte, Longueuil, CA;
UNIVERSITÉ DE MONTRÉAL, Montréal, CA;
Abstract
A novel method for human minor histocompatibility antigen (MiHA) discovery, novel MiHAs identified using this method, as well as uses of the novel MiHAs, are described. One of the features of the novel method is the inclusion of personalized translated transcriptome and/or exome in the database used for peptide identification by mass spectroscopy (MS). Candidate MiHAs are identified by comparing the personalized transcriptome and/or exome to a reference genome and/or to the transcriptome and/or exome of an HLA-matched subject.