The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2019
Filed:
Apr. 08, 2016
Applicant:
Ono Pharmaceutical Co., Ltd., Osaka, JP;
Inventors:
Ryo Suzuki, Osaka, JP;
Atsushi Hiramatsu, Osaka, JP;
Motoaki Tateyama, Fukui, JP;
Hideyuki Sasahara, Fukui, JP;
Assignee:
ONO PHARMACEUTICAL CO., LTD., Osaka, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 473/18 (2006.01); C07D 403/12 (2006.01); C07D 239/42 (2006.01); C07D 473/34 (2006.01);
U.S. Cl.
CPC ...
C07D 473/18 (2013.01); C07D 239/42 (2013.01); C07D 403/12 (2013.01); C07D 473/34 (2013.01); Y02P 20/55 (2015.11);
Abstract
According to the present invention, differently from well-known production methods, with the use of a different starting material, Ullmann condensation which may decrease the yield with an increase of a production scale can be avoided and thus 6-amino-9-[(3R)-1-(2-butynoyl)-3-pyrrolidinyl]-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one can be provided safely and stably with high reaction yield.