The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 26, 2019

Filed:

Jul. 07, 2017
Applicants:

Genentech, Inc., South San Francisco, CA (US);

Constellation Pharmaceuticals, Inc., Cambridge, MA (US);

Inventors:

Brian K. Albrecht, Cambridge, MA (US);

Daniel J. Burdick, South San Francisco, CA (US);

Alexandre Cote, Cambridge, MA (US);

Martin Duplessis, Cambridge, MA (US);

Christopher G. Nasveschuk, Cambridge, MA (US);

Alexander M. Taylor, Cambridge, MA (US);

Assignees:

GENETECH, INC., South San Francisco, CA (US);

CONSTELLATION PHARMACEUTICALS, INC., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 405/12 (2006.01); A61K 31/501 (2006.01); A61K 31/55 (2006.01); A61K 45/06 (2006.01); C07D 451/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); A61K 31/501 (2013.01); A61K 31/55 (2013.01); A61K 45/06 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 451/04 (2013.01);
Abstract

The invention relates to compounds of formula (I) and salts thereof: wherein R-Rhave any of the values defined in the specification. The compounds and salts are useful for treating PCAF mediated disorders and/or GCN5 mediated disorders. The invention also provides pharmaceutical compositions comprising a compound of formula (I), or a pharmaceutically acceptable salt thereof, as well as and methods of using said compounds, salts, or compositions in the treatment of various disorders.


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