The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 26, 2019

Filed:

Feb. 11, 2016
Applicants:

Icahn School of Medicine AT Mount Sinai, New York, NY (US);

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Washington, DC (US);

Inventors:

Samarjit Patnaik, Rockville, MD (US);

Mercedes Taylor, Berkeley, CA (US);

Raul Rolando Calvo, Rockville, MD (US);

Juan Jose Marugan, Rockville, MD (US);

Noel Southall, Rockville, MD (US);

Wei Zheng, Rockville, MD (US);

Marc Ferrer-Alegre, Rockville, MD (US);

Seameen Dehdasthi, Rockville, MD (US);

Patricia Dranchak, Rockville, MD (US);

Fannie Chen, New York, NY (US);

Yiannis Ioannou, New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 311/21 (2006.01); A61K 31/4164 (2006.01); A61K 31/44 (2006.01); C07D 207/335 (2006.01); C07D 213/46 (2006.01); C07D 233/64 (2006.01); A61K 31/165 (2006.01);
U.S. Cl.
CPC ...
C07C 311/21 (2013.01); A61K 31/165 (2013.01); A61K 31/4164 (2013.01); A61K 31/44 (2013.01); C07D 207/335 (2013.01); C07D 213/46 (2013.01); C07D 233/64 (2013.01);
Abstract

Methods and compositions for treating lysosomal storage disorders are disclosed. The methods involve administering a genus of benzenesulfonamides, particularly N-[3-(aminosulfonyl)phenyl]-benzamides and heteroarylamides. A genus of suitable compounds is shown in formula 1:


Find Patent Forward Citations

Loading…