The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 26, 2019

Filed:

Nov. 02, 2015
Applicants:

Board of Regents, the University of Texas System, Austin, TX (US);

Ingeneron, Inc., Houston, TX (US);

Inventors:

Andrew M Altman, Temple, TX (US);

Eckhard U. Alt, Houston, TX (US);

Michael E. Coleman, The Woodlands, TX (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/36 (2006.01); A61L 27/24 (2006.01); A61L 27/20 (2006.01); A61L 27/18 (2006.01); A61L 27/38 (2006.01); C12N 5/0775 (2010.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61L 27/3604 (2013.01); A61L 27/18 (2013.01); A61L 27/20 (2013.01); A61L 27/24 (2013.01); A61L 27/3662 (2013.01); A61L 27/3679 (2013.01); A61L 27/38 (2013.01); C12N 5/0667 (2013.01); A61K 35/12 (2013.01); A61L 2300/64 (2013.01); A61L 2400/06 (2013.01); A61L 2430/10 (2013.01); A61L 2430/22 (2013.01); C12N 2533/80 (2013.01);
Abstract

Methods are described for generating autologous tissue grafts, including generating grafts at the point of care, which include isolated cell populations that are enriched with stem cells and are mixed with biological fillers including hyaluronic acid and derivatives thereof. The hyaluronic acid localizes the cells to a desired injection site and stimulates collagen production thus enhancing the viability and the longevity of the graft.


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