The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2019
Filed:
Dec. 13, 2011
Daniel H. Zimmerman, Bethesda, MD (US);
Daniel H. Zimmerman, Bethesda, MD (US);
Cel-Sci, Corp, Vienna, VA (US);
Abstract
A vaccine for immunization against Type A influenza virus is provided having an immunologically effective amount of peptide constructs obtained by linking together two or more peptides based on or derived from different molecules, and methods for producing the same. The peptide constructs have the formula P-x-Por P-x-Pwhere Pis associated with Type A influenza highly conserved protein such as but not limited to M2e matrix protein, NP1 nucleoprotein, HA2 core 1, and HA2 core 2, where Pis a peptide construct causing a T1 directed immune response by a set or subset of T cells to which the peptide Pis attached or that binds to a dendritic cell or T cell receptor causing said set or subset of dendritic cell or T cells to which the peptide Pis attached to initiate and complete, an immune response, and x is a direct bond or divalent linker for covalently bonding Pand P.