The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2019
Filed:
Oct. 09, 2015
Applicant:
The Governing Council of the University of Toronto, Toronto, CA;
Inventors:
Assignee:
The Governing Council of the University of Toronto, Toronto, Ontario, CA;
Primary Examiner:
Int. Cl.
CPC ...
A61K 45/00 (2006.01); A61K 49/00 (2006.01); A61K 47/00 (2006.01); A61K 39/39 (2006.01); A61K 31/7024 (2006.01); C07H 11/04 (2006.01); G01N 33/50 (2006.01); A61K 45/06 (2006.01); A61K 39/095 (2006.01); C12Q 1/6876 (2018.01); C12Q 1/6897 (2018.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); A61K 31/7024 (2013.01); A61K 39/095 (2013.01); A61K 45/06 (2013.01); C07H 11/04 (2013.01); C12Q 1/6876 (2013.01); C12Q 1/6897 (2013.01); G01N 33/502 (2013.01); A61K 2039/55511 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/178 (2013.01); Y02A 50/403 (2018.01); Y02A 50/41 (2018.01); Y02A 50/412 (2018.01); Y02A 50/423 (2018.01);
Abstract
Novel methods and uses for modulating immune responses are provided. The methods and uses involve the use of a TIFA activator such heptose-1,7-5 bisphosphate or an analog or derivative thereof. The methods may be used to activate, inhibit or otherwise modify an immune response so as to either prevent or treat infectious or inflammatory diseases or cancer. Also provided are methods to identify compounds capable of modulating immune responses.