The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2019
Filed:
Jan. 24, 2017
Applicant:
Rochal Industries, Llc, San Antonio, TX (US);
Inventors:
Joseph Charles Salamone, San Antonio, TX (US);
Kelly Xiaoyu Chen Leung, San Antonio, TX (US);
Ann Beal Salamone, San Antonio, TX (US);
Katelyn Elizabeth Reilly, North Columbus, OH (US);
Assignee:
ROCHAL INDUSTRIES, LLC, San Antonio, TX (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/47 (2006.01); A61K 38/54 (2006.01); A61K 9/06 (2006.01); A61K 47/06 (2006.01); A61K 47/10 (2017.01); A61K 47/14 (2017.01); A61K 38/46 (2006.01); A61K 38/48 (2006.01); A61K 31/155 (2006.01); A61L 15/38 (2006.01); A61L 15/44 (2006.01); A61L 26/00 (2006.01); A61K 31/785 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/47 (2013.01); A61K 9/06 (2013.01); A61K 31/155 (2013.01); A61K 31/785 (2013.01); A61K 38/465 (2013.01); A61K 38/4873 (2013.01); A61K 38/54 (2013.01); A61K 47/06 (2013.01); A61K 47/10 (2013.01); A61K 47/14 (2013.01); A61L 15/38 (2013.01); A61L 15/44 (2013.01); A61L 26/0047 (2013.01); A61L 26/0066 (2013.01); C12Y 302/01 (2013.01); C12Y 302/01001 (2013.01); C12Y 302/01002 (2013.01); C12Y 304/22032 (2013.01); C12Y 304/24007 (2013.01); A61K 45/06 (2013.01); A61L 2300/206 (2013.01); A61L 2300/254 (2013.01); A61L 2300/402 (2013.01); A61L 2300/404 (2013.01); A61L 2300/45 (2013.01);
Abstract
A debridement enzyme for necrotic tissue is described that is not dependent upon proteolytic enzymatic activity but instead utilizes the amylase family of enzymes. The amylases (α-, β-, γ-amylase) are noted for the cleavage of the α-glycosidic bonds of polysaccharides, yielding lower molecular weight carbohydrate/sugar fragments. It has now been found that α-amylase is effective in the debridement of devitalized tissue.