The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2019
Filed:
Nov. 20, 2015
Applicant:
Atlanthera, Saint-Herblain, FR;
Inventors:
Maxim Egorov, Bouguenais, FR;
Jean-Yves Goujon, Derval, FR;
Ronan Le Bot, Nantes, FR;
Emmanuelle David, Port Saint Pere, FR;
Assignee:
Atlanthera, , FR;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/663 (2006.01); C07F 9/655 (2006.01); C07C 335/40 (2006.01); C07H 15/244 (2006.01); A61K 47/54 (2017.01);
U.S. Cl.
CPC ...
A61K 31/663 (2013.01); A61K 47/548 (2017.08); C07C 335/40 (2013.01); C07F 9/6552 (2013.01); C07H 15/244 (2013.01);
Abstract
The invention relates to hydrosoluble hydroxybisphosphonic derivatives of doxorubicin of formula (I) and the pharmaceutically acceptable salts thereof. The invention also relates to the use of said compounds as a drug, especially in the treatment of a bone tumour. The invention further relates to the pharmaceutical compositions comprising such compounds, the methods for the synthesis thereof and synthesis intermediates.