The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2019
Filed:
Nov. 08, 2017
Salk Institute for Biological Studies, La Jolla, CA (US);
The University of Sydney, Sydney, AU;
Ning Ding, Riverside, CA (US);
Michael Downes, San Diego, CA (US);
Christopher Liddle, Tura Beach, AU;
Ronald M. Evans, La Jolla, CA (US);
Nanthakumar Subramaniam, Wentworthville, AU;
Salk Institute for Biological Studies, La Jolla, CA (US);
The University of Sydney, Sydney, AU;
Abstract
The present disclosure provides compositions that include a nanoparticle and a compound that increases the biological activity of the vitamin D receptor (VDR) (e.g., a VDR agonist), and methods of using such compounds to increase retention or storage of vitamin A, vitamin D, and/or lipids by a cell, such as an epithelial or stellate cell. Such methods can be used to treat or prevent fibrosis.