The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2019
Filed:
Oct. 29, 2015
Applicant:
Hangzhou Weben Pharmaceuticals Inc, Hangzhou, Zhejiang, CN;
Inventors:
Rongzhen Xu, Hangzhou, CN;
Hongjian Jiang, Hangzhou, CN;
Assignee:
HANGZHOU WEBEN PHARMACEUTICALS INC, Hangzhou, Zhejiang, CN;
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/77 (2006.01); A61K 31/343 (2006.01); A61K 31/365 (2006.01); A61K 31/585 (2006.01); C07D 493/22 (2006.01); C07D 303/06 (2006.01); A61P 35/00 (2006.01); A61P 37/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/343 (2013.01); A61K 31/365 (2013.01); A61K 31/585 (2013.01); A61P 35/00 (2018.01); A61P 37/00 (2018.01); C07D 303/06 (2013.01); C07D 307/77 (2013.01); C07D 493/22 (2013.01);
Abstract
The present invention belongs to the field of natural medicines and medicinal chemistry, and relates to novel esterified amino acid derivatives of triptolide of general formula I and general formula II or pharmaceutically acceptable adducts, complexes, salts, and catabolites and metabolites thereof, preparation methods of these compounds, pharmaceutical compositions comprising the compound, and uses thereof in preparing drugs against tumors, immune diseases, or diseases related to abnormal expression of XPB or Pol II or oncogene c-myc.