The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2019
Filed:
Oct. 09, 2017
Tapestry Pharmaceuticals, Inc., Atlanta, GA (US);
TAPESTRY PHARMACEUTICALS, INC., Atlanta, GA (US);
Abstract
Provided herein are compounds, compositions containing the compounds, and methods for the treatment of cancer in a cancer patient. In particular, the compounds are made by a process comprising treating a first compound represented by either Formula G' or Formula M′: with a second compound of generalized formula RRC(OCH)and an acid selected from the group consisting of camphor sulfonic acid (CSA), p-toluene sulfonic acid (PTSA), hydrochloric acid (HCl) and acetic acid (AcOH), wherein Rand Rare each selected from H, an alkyl group, an olefinic group, an aromatic group, an O-alkyl group, an O-olefinic group, or an O-aromatic group; Ris an alkyl group, an olefinic group, or an aromatic group; Pis a hydroxyl protecting group; Pis H or an acid labile protecting group at the 7-O position; Ris H, alkyl group, olefinic or aromatic group; and Ris: H, alkyl group, olefinic or aromatic or is as defined in the specification.