The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 26, 2019

Filed:

Feb. 27, 2017
Applicant:

Corium International, Inc., Menlo Park, CA (US);

Inventors:

Parminder Singh, Union City, CA (US);

Eun Soo Lee, Redwood City, CA (US);

Amit K. Jain, Milpitas, CA (US);

Assignee:

Corium International, Inc., Menlo Park, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/18 (2006.01); A61K 47/14 (2017.01); A61K 47/02 (2006.01); A61K 9/00 (2006.01); A61K 9/70 (2006.01); A61K 31/137 (2006.01); A61K 47/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/18 (2013.01); A61K 9/0014 (2013.01); A61K 9/70 (2013.01); A61K 9/7023 (2013.01); A61K 9/7053 (2013.01); A61K 31/137 (2013.01); A61K 47/02 (2013.01); A61K 47/12 (2013.01); A61K 47/14 (2013.01);
Abstract

In an aspect of the invention, a composition for making a patch for the transdermal delivery of tamsulosin is provided. The composition comprises (a) at least about 1 wt % tamsulosin or a pharmaceutically acceptable salt of tamsulosin, (b) at least about 40 wt % polyisobutylene adhesive or hydrophobic synthetic rubber adhesive, (c) about 1-20 wt % of an aprotic solvent in which tamsulosin dissolves readily, (d) about 1-20 wt % of an unsaturated fatty acid or an alpha-hydroxy acid or a mixture of unsaturated fatty acids or alpha-hydroxy acids or of both unsaturated fatty acids and alpha-hydroxy acids, (e) a lipophilic permeation enhancer, and (f) a matrix modifier.


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