The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2019
Filed:
Jan. 26, 2012
Dirk Block, Bichl, DE;
Sara Arab, Toronto, CA;
Georg Hess, Mainz, DE;
Hendrik Huedig, Penzberg, DE;
Peter Liu, Toronto, CA;
Ursula-henrike Wienhues-thelen, Krailing, DE;
Dirk Block, Bichl, DE;
Sara Arab, Toronto, CA;
Georg Hess, Mainz, DE;
Hendrik Huedig, Penzberg, DE;
Peter Liu, Toronto, CA;
Ursula-Henrike Wienhues-Thelen, Krailing, DE;
Roche Diagnostics Operations, Inc., Indianapolis, IN (US);
Abstract
The disclosure relates to assessing heart failure in vitro by measuring the concentration of the marker mimecan in a sample, and optionally measuring in the sample the concentration of one or more other marker(s) of heart failure, and of assessing heart failure by comparing the concentration of mimecan and the one or more other marker(s) to reference concentrations of this (or these) marker(s) as established in a reference population. The one or more markers may be selected from the group comprising a natriuretic peptide marker, a cardiac troponin marker, and a marker of inflammation. Also disclosed are the use of mimecan as a marker protein in the assessment of heart failure, a marker combination comprising mimecan, and a kit for measuring mimecan.