The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 19, 2019

Filed:

Jun. 06, 2016
Applicant:

Integenx Inc., Pleasanton, CA (US);

Inventors:

Philip Justus Wunderle, Oakland, CA (US);

Chungsoo Charles Park, Redwood City, CA (US);

David King, Menlo Park, CA (US);

Dennis Lehto, Santa Clara, CA (US);

Assignee:

IntegenX, Inc., Pleasanton, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6874 (2018.01); C12Q 1/686 (2018.01); B01L 3/00 (2006.01); F16K 99/00 (2006.01); B01L 7/00 (2006.01); B01F 13/00 (2006.01); B01F 13/02 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6874 (2013.01); B01L 3/502738 (2013.01); C12Q 1/686 (2013.01); F16K 99/0015 (2013.01); F16K 99/0034 (2013.01); B01F 13/0059 (2013.01); B01F 13/02 (2013.01); B01L 3/502753 (2013.01); B01L 7/52 (2013.01); B01L 2200/04 (2013.01); B01L 2200/0668 (2013.01); B01L 2200/16 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0887 (2013.01); B01L 2300/123 (2013.01); B01L 2400/043 (2013.01); B01L 2400/0478 (2013.01); B01L 2400/0655 (2013.01); F16K 2099/0078 (2013.01); F16K 2099/0084 (2013.01);
Abstract

This disclosure provides, among other things, a cartridge comprising: (a) a cartridge body comprising a malleable material and having, disposed on a surface of the body, at least one valve body comprising a valve inlet and a valve outlet, each fluidically connected to a fluidic channel; and (b) a layer comprising a deformable material bonded to a surface of the cartridge body and sealing the at least one valve body at points of attachment, thereby forming at least one valve; wherein the at least one valve body is depressed in the cartridge body relative to the points of attachment and wherein the deformable material covering the at least one valve body retains sufficient elasticity after deformation such that in a ground state the valve is open. Also disclosed is an instrument comprising a cartridge interface and a cartridge as described herein engaged with the cartridge interface, wherein (II) the cartridge interface comprises: (A) at least one mechanical actuator, each mechanical actuator positioned to actuate a valve; and (B) at least one motor operatively coupled to actuate a mechanical actuator toward or away from a valve.


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