The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 19, 2019

Filed:

Dec. 21, 2015
Applicant:

Invista North America S.á.r.l., Wilmington, DE (US);

Inventors:

Alexander Brett Foster, Yarm, GB;

Mariusz Kamionka, Cleveland, GB;

Nadia Fatma Kadi, Cleveland, GB;

Adriana Leonora Botes, Rosedale East, GB;

Alex Van Eck Conradie, Eaglescliffe, GB;

Assignee:

INVISTA North America S.á.r.l., Wilmington, DE (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 1/00 (2006.01); C12N 9/10 (2006.01); C12P 7/24 (2006.01); C12P 7/26 (2006.01); C12P 7/42 (2006.01); C12P 13/00 (2006.01); C12P 19/32 (2006.01); C07H 19/207 (2006.01);
U.S. Cl.
CPC ...
C12P 19/32 (2013.01); C07H 1/00 (2013.01); C07H 19/207 (2013.01); C12N 9/1029 (2013.01); C12P 7/24 (2013.01); C12P 7/26 (2013.01); C12P 7/42 (2013.01); C12P 13/001 (2013.01); C12P 13/005 (2013.01); C12Y 203/01 (2013.01);
Abstract

This document describes materials and methods for, for example, producing 6-hydroxyhexanoic acid using a β-ketothiolase or synthase and an alcohol O-acetyltransferase to form a 6-acetyloxy-3-oxohexanoyl-CoA intermediate. This document describes biochemical pathways for producing 6-hydroxyhexanoic acid using a β-ketothiolase or synthase and an alcohol O-acetyltransferase to form a 6-acetyloxy-3-oxohexanoyl-CoA intermediate. 6-hydroxyhexanoic acid can be enzymatically converted to adipic acid, caprolactam, 6-aminohexanoic acid, hexamethylenediamine or 1,6-hexanediol. This document also describes recombinant hosts producing 6-hydroxyhexanoic acid as well as adipic acid, caprolactam, 6-aminohexanoic acid, hexamethylenediamine and 1,6-hexanediol.


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