The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 19, 2019

Filed:

Dec. 22, 2017
Applicant:

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

Inventors:

Juan G. Santiago, Stanford, CA (US);

Lewis A. Marshall, Pleasanton, CA (US);

Anita Rogacs, Los Altos, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C12Q 1/6806 (2018.01); B01L 3/00 (2006.01); B01D 57/02 (2006.01); G01N 27/447 (2006.01);
U.S. Cl.
CPC ...
C12N 15/101 (2013.01); B01D 57/02 (2013.01); B01L 3/502715 (2013.01); B01L 3/502723 (2013.01); B01L 3/502738 (2013.01); C12Q 1/6806 (2013.01); B01L 2200/027 (2013.01); B01L 2200/0621 (2013.01); B01L 2200/0631 (2013.01); B01L 2200/0684 (2013.01); B01L 2200/10 (2013.01); B01L 2300/0838 (2013.01); B01L 2300/0858 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/12 (2013.01); B01L 2300/165 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0421 (2013.01); B01L 2400/0688 (2013.01); B01L 2400/086 (2013.01); B01L 2400/088 (2013.01); G01N 27/44791 (2013.01);
Abstract

Various aspects of the present disclosure are directed toward methods and apparatuses for interacting a first liquid and a second liquid in one or more fluidic channels of a capillary structure. The methods and apparatuses can include providing at least one capillary barrier that positions a meniscus of the first liquid at a fluid-interface region using capillary forces within the capillary structure. Additionally, a path is provided along one of the channels for the second liquid to flow toward the fluid-interface region. Additionally, gas pressure is released, via a gas-outflow port, from the fluid-interface region while flow of the first liquid is arrested. Further, the first liquid and the second liquid contact in the fluid-interface region with the capillary barrier holding the first liquid at the fluid-interface region.


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