The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2019
Filed:
May. 29, 2015
Applicant:
Kyoto University, Kyoto-shi, JP;
Inventors:
Norio Nakatsuji, Kyoto, JP;
Itsunari Minami, Kyoto, JP;
Assignee:
KYOTO UNIVERSITY, Kyoto-Shi, Kyoto, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/12 (2015.01); C12N 5/077 (2010.01); C12N 5/10 (2006.01); C07D 277/82 (2006.01); C07D 513/04 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0657 (2013.01); C12N 5/10 (2013.01); C07D 277/82 (2013.01); C07D 513/04 (2013.01); C12N 2501/11 (2013.01); C12N 2501/415 (2013.01); C12N 2501/727 (2013.01); C12N 2506/45 (2013.01);
Abstract
The present invention provides a method for inducing cardiac differentiation of a pluripotent stem cell, which comprises the steps of (1) culturing a pluripotent stem cell in a medium containing a WNT signaling activator and a PKC activator and (2) culturing the cell after the step (1) in a medium containing a WNT signaling inhibitor, a Src inhibitor, and an EGFR inhibitor.