The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2019
Filed:
Aug. 19, 2015
Applicant:
Kyowa Hakko Kirin Co., Ltd, Tokyo, JP;
Inventors:
Motoo Yamasaki, Shizuoka, JP;
Yasuhisa Shiraishi, Tokyo, JP;
Assignee:
KYOWA HAKKO KIRIN CO., LTD, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 47/68 (2017.01); A61K 47/61 (2017.01); A61K 47/50 (2017.01); A61K 47/60 (2017.01); A61K 47/54 (2017.01); C07K 16/00 (2006.01); C07K 16/32 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2863 (2013.01); A61K 47/6849 (2017.08); C07K 16/00 (2013.01); C07K 16/32 (2013.01); A61K 47/50 (2017.08); A61K 47/549 (2017.08); A61K 47/60 (2017.08); A61K 47/61 (2017.08); A61K 47/68 (2017.08); A61K 47/6803 (2017.08); C07K 2317/14 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/52 (2013.01); C07K 2317/522 (2013.01);
Abstract
The present invention relates to an antibody or antibody fragment comprising novel Cys residue, to which a hydrophilic macromolecular group or amphipathic macromolecular group can be bound at a high efficiency. In addition, the present invention relates to a monoclonal antibody modified product or an antibody fragment modified product in which cysteine residue is chemically modified.