The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2019
Filed:
Feb. 05, 2015
Applicant:
Scancell Limited;
Inventors:
Linda Gillian Durrant, Nottingham, GB;
Victoria Anne Brentville, Nottingham, GB;
Rachael Louise Metheringham, Nottingham, GB;
Assignee:
Scancell Limited, Nottingham, Nottinghams, GB;
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 14/47 (2006.01); C07K 7/08 (2006.01); C07K 7/06 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4748 (2013.01); A61K 39/0011 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); G01N 33/57496 (2013.01); G01N 2333/47 (2013.01); G01N 2333/978 (2013.01);
Abstract
Anti-tumor immune responses to modified self-epitopes. The present invention relates to the use of tumor-associated epitopes in medicine and in particular in the treatment of cancer. The epitopes stimulate an immune reaction against the tumor and have a modification selected from deimination of arginine to citrulline, nitration of tyrosine, oxidation of tryptophan and deamination of glutamine or asparagine. The invention also relates to nucleic acids comprising sequences that encode such epitopes for use in the treatment of cancer.