The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2019
Filed:
Dec. 06, 2016
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Washington, DC (US);
The Penn State Research Foundation, University Park, PA (US);
Frank J. Gonzalez, Bethesda, MD (US);
Changtao Jiang, Beijing, CN;
Cen Xie, Rockville, MD (US);
Andrew D. Patterson, State College, PA (US);
Fei Li, Rockville, MD (US);
James B. Mitchell, Damascus, MD (US);
Shantu Amin, Union City, NJ (US);
Dhimant Desai, Mechanicsburg, PA (US);
The United States of America, As represented by the Secretary, Department of Health and Human Services, Washington, DC (US);
The Penn State Research Foundation, University Park, PA (US);
Abstract
Disclosed are inhibitors of the farnesoid X receptor, for example of formula (I), wherein R, R, R, X, Y, Z, m, and n are as defined herein, which are useful in treating or preventing obesity, type 2 diabetes/insulin resistance and non-alcoholic fatty liver disease in a mammal in need thereof. Also disclosed is a composition comprising a pharmaceutically suitable carrier and at least one compound of the invention, a method of method of inhibiting a farnesoid X receptor in a mammal, and a method of treating or preventing obesity in a mammal.