The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 19, 2019

Filed:

May. 26, 2016
Applicant:

Jiangsu Tasly Diyi Pharmaceutical Co., Ltd., Jiangsu, CN;

Inventors:

Guocheng Wang, Jiangsu, CN;

Huimin Wu, Jiangsu, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/6561 (2006.01); A61P 31/18 (2006.01); A61P 31/20 (2006.01); A61P 31/12 (2006.01); A61K 31/675 (2006.01);
U.S. Cl.
CPC ...
C07F 9/65616 (2013.01); A61K 31/675 (2013.01); A61P 31/12 (2018.01); A61P 31/18 (2018.01); A61P 31/20 (2018.01); C07F 9/6561 (2013.01);
Abstract

The present invention relates to a tenofovir monobenzyl ester phosphamide prodrug, preparation method and pharmaceutical use thereof. Specifically, the present invention relates to a compound of general formula (X), or isomer, pharmaceutically-acceptable salt, hydrate or solvate thereof, preparation method and use thereof in the preparation of drugs for treating viral infectious diseases, preferably AIDS infection, hepatitis B or diseases caused by hepatitis B virus.


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