The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2019
Filed:
May. 29, 2015
Applicant:
Ieo—instituto Europeo Di Oncologia S.r.l., Milan, IT;
Inventors:
Paola Vianello, Milan, IT;
Mario Varasi, Milan, IT;
Ciro Mercurio, Legnano, IT;
Anna Cappa, Visso, IT;
Giuseppe Meroni, Milan, IT;
Manuela Villa, Lurago d'Erba, IT;
Antonello Mai, Rome, IT;
Sergio Valente, Cassino, IT;
Assignee:
Istituto Europeo di Oncologia S.r.l., Milan, IT;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/421 (2006.01); A61K 31/445 (2006.01); A61K 31/495 (2006.01); A61K 31/5375 (2006.01); A61K 45/06 (2006.01); C07D 211/14 (2006.01); C07D 211/34 (2006.01); C07D 241/04 (2006.01); C07D 263/22 (2006.01); C07D 265/30 (2006.01); C07D 295/155 (2006.01);
U.S. Cl.
CPC ...
C07D 295/155 (2013.01); A61K 31/421 (2013.01); A61K 31/445 (2013.01); A61K 31/495 (2013.01); A61K 31/5375 (2013.01); A61K 45/06 (2013.01); C07D 211/14 (2013.01); C07D 211/34 (2013.01); C07D 241/04 (2013.01); C07D 263/22 (2013.01); C07D 265/30 (2013.01);
Abstract
The present disclosure relates to cyclopropyl compounds of general formula (I), wherein R, and Rare as defined in the specification. The present application also relates to pharmaceutical compositions containing such compounds and to their use in therapy.