The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 19, 2019

Filed:

Jun. 16, 2015
Applicant:

Gnubio, Inc., Cambridge, MA (US);

Inventors:

Adam R. Abate, San Francisco, CA (US);

Sepehr Kiani, Watertown, MA (US);

Assignee:

Bio-Rad Laboratories, Inc., Hercules, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 15/10 (2006.01); G01N 15/14 (2006.01); B01L 3/02 (2006.01); C12M 3/06 (2006.01); C12M 1/00 (2006.01); C12Q 1/6806 (2018.01); C12Q 1/68 (2018.01); G01N 15/02 (2006.01); G01N 35/10 (2006.01); G01N 27/447 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502784 (2013.01); B01L 3/0241 (2013.01); B01L 3/5027 (2013.01); C12M 23/16 (2013.01); C12M 47/04 (2013.01); C12Q 1/6806 (2013.01); G01N 15/10 (2013.01); G01N 15/14 (2013.01); B01L 3/502746 (2013.01); B01L 3/502761 (2013.01); B01L 3/502776 (2013.01); B01L 3/502792 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/0883 (2013.01); B01L 2400/043 (2013.01); B01L 2400/0409 (2013.01); B01L 2400/0424 (2013.01); B01L 2400/0433 (2013.01); B01L 2400/0436 (2013.01); B01L 2400/0439 (2013.01); B01L 2400/0442 (2013.01); B01L 2400/0454 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/0622 (2013.01); B01L 2400/084 (2013.01); G01N 15/0255 (2013.01); G01N 27/44791 (2013.01); G01N 2015/0288 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/1081 (2013.01); G01N 2035/1034 (2013.01);
Abstract

This invention pertains to a new microfluidic device and the method of using it to sort droplets. The method comprises (a) providing a plurality of droplets flowing in a microfluidic channel, wherein the plurality of droplets comprise desired droplets and undesired droplet (b) identifying desired droplets in the plurality of droplets, (c) changing volume of the desired droplets relative to volume of the undesired droplets such that at least some of the desired droplets have a different volume than the undesired droplets, and (d) passively sorting the desired droplets having the different volume from the undesired droplets.


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