The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 19, 2019

Filed:

Nov. 02, 2015
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Pei-Yu E. Chiou, Los Angeles, CA (US);

Ting-Hsiang S. Wu, Culver City, CA (US);

Sung-Yong Park, Kent Vale, SG;

Michael A. Teitell, Tarzana, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G05D 11/13 (2006.01); B01J 13/04 (2006.01); G01N 29/24 (2006.01); G01N 15/10 (2006.01); G01N 21/64 (2006.01); G01N 15/14 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502715 (2013.01); B01J 13/04 (2013.01); B01L 3/502761 (2013.01); B01L 3/502784 (2013.01); G01N 29/2418 (2013.01); G05D 11/13 (2013.01); B01L 2200/0636 (2013.01); B01L 2200/0647 (2013.01); B01L 2200/0668 (2013.01); B01L 2200/0673 (2013.01); B01L 2300/0816 (2013.01); B01L 2400/0403 (2013.01); B01L 2400/0442 (2013.01); G01N 15/10 (2013.01); G01N 21/64 (2013.01); G01N 2015/1481 (2013.01); G01N 2291/02433 (2013.01); Y10T 137/0318 (2015.04); Y10T 137/2496 (2015.04);
Abstract

Methods and devices for the formation of droplets of a first fluid in a second fluid and the encapsulation of particles or cells within such droplets are disclosed. Impetus for droplet formation is provided by the creation of a transient bubble, which may be induced using a pulsed laser. Droplet volume and the frequency at which droplets are formed can be controlled by modulation of the pulsed laser. The disclosed methods and devices are particularly suitable for use in microfluidic devices.


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