The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 19, 2019

Filed:

Aug. 22, 2013
Applicants:

Fraunhofer-gesellschaft Zur Föderung Der Angewandten Forschung E.v., München, DE;

Albert-ludwigs-universität Freiburg, Freiburg, DE;

Inventors:

Ingo Grunwald, Lilienthal, DE;

Katharina Richter, Bremen, DE;

Arkadiusz Miernik, Freiburg, DE;

Martin Schoenthaler, Freiburg, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61L 24/08 (2006.01); A61L 24/00 (2006.01); A61L 24/04 (2006.01); A61L 24/02 (2006.01); A61B 17/22 (2006.01); A61B 17/00 (2006.01);
U.S. Cl.
CPC ...
A61L 24/08 (2013.01); A61L 24/0031 (2013.01); A61L 24/02 (2013.01); A61L 24/04 (2013.01); A61B 17/22 (2013.01); A61B 2017/00876 (2013.01); A61B 2017/22082 (2013.01); A61L 2430/26 (2013.01);
Abstract

Primarily described are gel-forming systems, consisting of or comprising a composition (A), comprising one or several cationically crosslinkable polymer(s), and a composition (B), comprising one or several crosslinking agent(s) for crosslinking the cationically crosslinkable polymer(s) for use in a method for removing urinary calculi and/or fragments thereof, more particularly kidney stones and/or fragments thereof, from a region of the urinary tract, more particularly a kidney, that contains urinary calculi and/or fragments thereof, more particularly kidney stones and/or fragments thereof, that are to be removed, with the following steps: (i) providing the compositions (A) and (B), (ii) introducing the compositions (A) and (B) into a region of the urinary tract, more particularly the kidney, that contains urinary calculi and/or fragments thereof, more particularly kidney stones and/or fragments thereof, that are to be removed, under conditions enabling crosslinking of the cationically crosslinkable polymer(s) upon contact of composition (A) with composition (B) so that a crosslinked gel is formed that partly or fully surrounds the urinary calculi and/or fragments thereof, more particularly kidney stones and/or fragments thereof, that are to be removed, (iii) removing the crosslinked gel together with the urinary calculi and/or fragments thereof, more particularly kidney stones and/or fragments thereof, that are surrounded by it from the urinary tract, more particularly the kidney.


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