The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2019
Filed:
Apr. 16, 2015
Applicant:
Kyowa Hakko Kirin Co., Ltd., Tokyo, JP;
Inventors:
Shinichi Uchida, Tokyo, JP;
Tomoyuki Kanda, Tokyo, JP;
Assignee:
KYOWA HAKKO KIRIN CO., LTD., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 10/00 (2006.01); A61K 39/00 (2006.01); A61K 49/00 (2006.01); C07K 16/18 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0008 (2013.01); A61B 5/4088 (2013.01); C07K 16/18 (2013.01); G01N 33/6896 (2013.01); A61B 2010/0077 (2013.01); A61B 2503/40 (2013.01); A61B 2503/42 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01);
Abstract
The problem is to provide a method that can quickly and efficiently evaluate the toxicity of human cerebrospinal fluid (CSF) with small amounts of human CSF. The problem is solved by a method comprising administering human CSF into the cerebral ventricle of a rodent such as a mouse, and evaluating the cognitive function of the rodent by using a behavioral pharmacological technique.